Table 4 The pharmacokinetic parameters of myrislignan in mice following oral or intraperitoneal administration (n = 6)

K_el (h^− 1)

1.19 ± 0.443

0.366 ± 0.0789

T_1/2 (h)

0.692 ± 0.386

1.97 ± 0.426

T_max (h)

0.167 ± 0.0915

1.04 ± 1.45

C_max (ng/mL)

3870 ± 1200

105 ± 72.3

Cl_F_obs(mL/hr/kg)

45,123 ± 11,936

302,900 ± 442,668

Vz_F_obs(mL/kg)

24,198 ± 5987

970,149 ± 199,518

AUC_0 − t (h/ng/mL)

2050 ± 532

157 ± 55.1

AUC_{0 − inf} (h/ng/mL)

2060 ± 536

162 ± 52.9

AUMC_last (hr*hr*ng/mL)

1006 ± 227

457 ± 240

MRT_0 − t (h)

0.457 ± 0.0499

2.19 ± 0.841

MRT_{0 − inf} (h)

0.466 ± 0.0485

2.57 ± 0.858

 F* = 1.97 %