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Table 3 Stability of myrislignan in mouse plasma samples under various conditions (n = 6)

From: Determination of myrislignan levels in BALB/c mouse plasma by LC-MS/MS and a comparison of its pharmacokinetics after oral and intraperitoneal administration

Storage conditions

Concentration (ng/mL)

Accuracy ± SD (%)

RSD (%)

Ambient temperature for 24 h

15

92.22 ± 6.02

6.53

400

99.24 ± 4.32

4.35

800

108.98 ± 3.63

3.33

At -20 °C for 60 days

15

104.21 ± 7.62

7.31

400

102.35 ± 6.54

6.39

800

110.02 ± 3.84

3.49

At 4 °C in the autosampler for 24 h

15

106.26 ± 5.43

5.11

400

108.49 ± 1.98

1.83

800

99.63 ± 7.67

7.70

3 Freeze-thaw cycles

15

93.02 ± 3.78

4.06

400

97.85 ± 5.30

5.42

800

101.73 ± 6.87

6.75