Skip to main content

Table 3 Stability of myrislignan in mouse plasma samples under various conditions (n = 6)

From: Determination of myrislignan levels in BALB/c mouse plasma by LC-MS/MS and a comparison of its pharmacokinetics after oral and intraperitoneal administration

Storage conditions Concentration (ng/mL) Accuracy ± SD (%) RSD (%)
Ambient temperature for 24 h 15 92.22 ± 6.02 6.53
400 99.24 ± 4.32 4.35
800 108.98 ± 3.63 3.33
At -20 °C for 60 days 15 104.21 ± 7.62 7.31
400 102.35 ± 6.54 6.39
800 110.02 ± 3.84 3.49
At 4 °C in the autosampler for 24 h 15 106.26 ± 5.43 5.11
400 108.49 ± 1.98 1.83
800 99.63 ± 7.67 7.70
3 Freeze-thaw cycles 15 93.02 ± 3.78 4.06
400 97.85 ± 5.30 5.42
800 101.73 ± 6.87 6.75