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Table 1 Patient Characteristics of Dogs Diagnosed with Pancreatic Carcinoma Treated with Toceranib Phosphate

From: Toceranib phosphate (Palladia) for the treatment of canine exocrine pancreatic adenocarcinoma

Case Number

Breed

Gender

Diagnosis Via

Toceranib Dose (mg)

Best Response

Imaging used to assess response

Toceranib-specific Survival Time (days)

Cause of Death

1

Golden Retriever

MC

Cytology

2.2

PD

Clinical response

52

Pancreatic Carcinoma

2

Golden Retriever

FS

Cytology/Histopathology

2.8

SD

AUS and CXR every 8–12 weeks

302

Pancreatic Carcinoma

3

Beagle

FS

Histopathology

2.7

*

N/A

LTF: 82

Lost to follow-up

4

Beagle

FS

Histopathology

2.4

*

N/A

14

Pancreatic Carcinoma

5

Shih Tzu

FS

Cytology

2.8

PR

AUS

97

Lost to follow-up

6

Pitbull

MC

Histopathology

2.3

SD

AUS

Alive at Data Capture (05/12/2021): 506

 N/A

7

Old English Sheepdog

FS

Cytology

2.2

PD

AUS

17

Unknown

8

Irish Terrier

FS

Histopathology

2.5

SD

Clinical response

301

Pancreatic Carcinoma

  1. AUS Abdominal Ultrasound, CXR Chest radiographs, FS Female spayed, LTF Lost to follow-up, MC male castrated, PD progressive disease, PR partial remission, SD stable disease
  2. *Toceranib used in the microscopic disease setting