Table 1 Variants identified in Boxers dogs with SCCED in genes likely to have a possible role in corneal disease and corneal wound healing
Chromosomal location | Gene | Reference allele | Variant allele | Gene location |
|---|---|---|---|---|
19: 50605253 | KIF5C | C | A | Intronic |
19: 50602128 | KIF5C | A | T | Intronic |
19: 50543167 | KIF5C | T | A | Intronic |
19: 50546726 | KIF5C | C | A | Intronic |
32: 22284093 | EMCS | A | G | Missense |
37: 29701267 | Serpine 2 | A | G | Splice Site |
9: 49015931 | NOTCH1 | G | A | Missense |
9: 31453999 | NOG | gtgtgtgtgtgtgt gtgtgtgtgtgtgtga | Deletion |