Spectrophotometric assays for evaluation of Reactive Oxygen Species (ROS) in serum: general concepts and applications in dogs and humans

Table 3 Studies in which the ferric-xylenol orange (FOX) assay was applied in serum samples of dogs

Situation studied	Concentrations (μmol t-Bu-OOH Equiv./L, unless stated otherwise)	Reference
Sarcoptic mange	Control: 6.9 μmol H₂O₂ Equiv./L Diseased: 15.5 μmol H₂O₂ Equiv./L	[71]
Idiopathic inflammatory bowel disease	Control: 72.0 Diseased: 148.0	[26]
Atopic dermatitis	Control: 65.0 Diseased: 82.0	[92]
Canine monocytic ehrlichiosis	Control: ± 80.0 Subclinical disease: ± 80.0 Clinical disease: ± 85.0	[91]
Serum pools from healthy Beagle dogs	76.0–94.6	[66]

ISSN: 1746-6148