Groups | Dose (TCID50) | Virus shedding day (post challenge) | Survival rate | Virus shedding | |
---|---|---|---|---|---|
Pathogenic testing in piglets | (A)PRV-GD2013 | 105 | 2 to death | 0/5 | 5/5 |
(B)PRV-GD2013-ΔgI/gE | 105 | N | 5/5 | 0/5 | |
(C)DMEM | 2 ml | N | 5/5 | 0/5 | |
Immunization and challenge experiments | (A)PRV-GD2013-ΔgI/gE | 105 | N | 5/5 | 0/5 |
(B)PRV-GD2013-ΔgI/gE | 104 | N | 5/5 | 0/5 | |
(C)PRV-GD2013-ΔgI/gE | 103 | 4–8 | 5/5 | 1/5 | |
(D)Bartha-K61 | 105 | 3–9 | 5/5 | 4/5 | |
(E)DMEM | 2 ml | 2 to death | 2/5 | 5/5 |