Fig. 1
From: Topical ophthalmic atropine in horses, pharmacokinetics and effect on intestinal motility
Semi-logarithmic spaghetti plots of the plasma disposition curves of atropine over 3 h after a single dose administration of atropine as 1 mg atropine sulfate as an intravenous (IV) bolus dose (left plot) and as a bolus dose (same dose as for IV with a 0.1 mL volume) administered topically using an ophthalmic solution (eye drops) (right plot). The lower limit of quantification for the analytical method was 0.05 μg/L.