Fig. 6
From: Aggressive squamous cell carcinoma of the cranium of a dog
Keratinizing squamous cell carcinoma of the skull. a Nests and trabeculae composed of squamous neoplastic cells showing marked pleomorphism. Concentric lamellae of keratin (keratin pearls - arrows) are visible in the center of the larger nest. (HE, 100x). b Infiltrative squamous nests invading the bone tissue (arrows) (HE, 100x)