Fig. 4

Comparison of immune response related pathways in tonsils at 42 days post infection between the NanoString and RNA-seq data. Comparison of the immune response related pathways that include differentially expressed genes for pigs infected with the KS06 versus the NVSL PRRSV isolate (K/N) based on the model without cell enrichments. The expression values of genes with a false discovery rate < 0.1 were used to calculate -log(p-values) and z-scores for each pathway. Orange color (z-score ≥ 2) and blue color (z-score ≤ − 2) indicate activation and inhibition of predicted pathways, respectively. The more intense these colors, the higher the absolute z-scores