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Table 4 Predicted flux and Kp for chloramphenicol in a solution of ARS through cane toad skin

From: Predicting in vivo absorption of chloramphenicol in frogs using in vitro percutaneous absorption data

LogP

Skin Region

Flux (μg/cm2/h)

Kp (cm.h− 1; × 10− 3)

In vitro (predicted)

In vitro (predicted)

1.14

Dorsal

23.406

3.675

1.14

Ventral thoracic

20.764

3.254

1.14

Ventral pelvic

26.006

3.956

  1. Predictions from models developed in vitro for three model chemicals and reported in [35]