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Table 3 Effect of Clostridium perfringens and Eimeria meleagrimitis on frequency of severe intestinal lesions

From: Developing an experimental necrotic enteritis model in turkeys - the impact of Clostridium perfringens, Eimeria meleagrimitis and host age on frequency of severe intestinal lesions

Study variableStudy variable levelEM dose1Hours after EM2ExperimentsNo. of birds (gut contents)% score3OPG3
CP4No10–20125–1451,4,7,9533 (6)6.1c5.8e
3-wk-oldYes10–20125–1451,4,7,9557 (8)12.3c6.0e
 No10–20125–145924 (4)4.2c5.8e
 Yes10–20125–145923 (4)8.7c5.5e
5-wk-oldNo10–20125–145924 (4)41.7c5.3e
 Yes10–20125–145925 (4)76.0d5.7e
EM dose60.25–1.6121–1682,3101 (21)6.9a5.6a
(thousands)5123–1711,468 (15)25.0b5.4a
 15–20123–1711,468 (15)27.9b5.5a
Low dose0.25–1.6121–1232,344 (9)< 2.3a4.5a
dynamics 1452,345 (9)2.3a6.1b
  168312 (3)46.2b6.2b
High dose5–20123–1291,445 (12)73.3a6.5a
dynamics 145–1471,444 (6)7< 2.3b5.2b
  169–1711,447 (12)6.4b4.9b
  1. 1Numbers (in thousands) of inoculated Eimeria meleagrimitis oocysts per bird, 2 Number of hours elapsed between Eimeria meleagrimitis inoculation and examination of turkeys, 3Median log10 of oocysts per gram intestinal contents, based on samples of contents from posterior small intestine (from Meckel’s diverticulum to caeco-intestinal junction), caeca and colorectum from Eimeria meleagrimitis-inoculated turkeys 4Clostridium perfringens inoculation, 5 OPG counts based on data from experiments 1, 7 and 9, 6 3-week-old Eimeria meleagrimitis-inoculated and Clostridium perfringens-inoculated turkeys, 7 OPG data only from experiment 4
  2. a-bDunn’s test with Bonferroni adjustment of p-values for multiple comparisons. Different letters indicate significant (p < 0.05) difference, c-dPearson chi-square test. Different letters indicate significant (p < 0.05) difference, eKruskal-Wallis rank test. Different letters indicate significant (p < 0.05) difference