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Table 1 Quantum dot labeled ECFCs in week 1 biopsies

From: Cell engraftment, vascularization, and inflammation after treatment of equine distal limb wounds with endothelial colony forming cells encapsulated within hydrogel microspheres

 

ECFC

ECFC/MS

P value

# Wounds with QD+ cells at week 1

3/6

6/6

0.27

QD+ cells per cryosection

ALL (Median [IQR])

11 [3–24]

21 [9–42]

0.14

QD+ cells per cryosection

LOW (Median [IQR])

5.5 [3–20.25]

27 [11.75–44.5]

0.02

QD+ cells per cryosection

HIGH (Median [IQR])

19 [15.75–35.75]

10 [1–21]

0.38

  1. 10 slides with 2 sections per slide per biopsy were used to quantify the number of quantum dot (QD) positive ECFCs in week 1 biopsy samples. Each horse had 1 wound per treatment biopsied at week 1. ALL = all cell-treated wounds from week 1 biopsies from both phases of study. LOW = wounds from Phase 1 with 8 mil cells/wound. HIGH = wounds from Phase 2 with 12–16 mil cells/wound. IQR = interquartile range. Significant P values are in bold, italicized text.