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Table 2 Regional standardized uptake value ratios (SUVRs) for 18F-flutemetamol in normal canine brain regions at different scan times

From: Temporal and anatomical distribution of 18F-flutemetamol uptake in canine brain using positron emission tomography

 

SUVRs

Region

30 min post-injection

60 min post-injection

90 min post-injection

Frontal cortex

1.23 ± 0.11

1.27 ± 0.30

1.38 ± 0.33

Parietal cortex

1.16 ± 0.12

1.15 ± 0.23

1.23 ± 0.25

Temporal cortex

1.18 ± 0.09

1.07 ± 0.20

1.06 ± 0.18

Occipital cortex

0.99 ± 0.06

0.95 ± 0.10

1.03 ± 0.14

Anterior cingulate cortex

1.33 ± 0.10

1.34 ± 0.27

1.32 ± 0.33

Posterior cingulate cortex

1.34 ± 0.10

1.28 ± 0.16

1.32 ± 0.28

Midbrain

2.35 ± 0.35a,b,c

2.13 ± 0.63a

2.03 ± 0.54

Pons

2.52 ± 0.48a,b,c,d

2.65 ± 0.91a,b,c

2.57 ± 0.89a,b

Medulla oblongata

1.88 ± 0.25a

2.10 ± 0.47a

2.12 ± 0.68a

Cerebral white matter

1.81 ± 0.24a

2.22 ± 0.65a,b

2.47 ± 0.72*,a,b

Composite†

1.25 ± 0.09

1.26 ± 0.20

1.27 ± 0.25

  1. Values are SUVRs, using the cerebellar cortex as the reference region and are expressed as mean ± SD. Data were obtained at 30, 60, and 90 min post-tracer injection (n = 6). Superscripts * within rows indicate that the mean SUVR differs at 90 min as compared with that at 0 min by P < 0.05; a, b, c, d within columns indicate the mean SUVRs differ from that at the occipital cortex, temporal cortex, parietal cortex, and frontal cortex by P < 0.05; †Values for the composite comprise the average SUVRs for the frontal, parietal, temporal, occipital, anterior cingulate, and posterior cingulate cortices; SUVR Standardized uptake value ratio