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Table 1 Regional standardized uptake values (SUVs) for 18F-flutemetamol in normal canine brain regions at different scan times

From: Temporal and anatomical distribution of 18F-flutemetamol uptake in canine brain using positron emission tomography

 

SUVs

Region

30 min post-injection

60 min post-injection

90 min post-injection

Frontal cortex

0.65 ± 0.14

0.39 ± 0.09

0.29 ± 0.07*

Parietal cortex

0.62 ± 0.15

0.35 ± 0.08

0.26 ± 0.06*

Temporal cortex

0.63 ± 0.14

0.33 ± 0.08

0.22 ± 0.05*

Occipital cortex

0.53 ± 0.14

0.29 ± 0.07

0.22 ± 0.05*

Anterior cingulate cortex

0.70 ± 0.15

0.41 ± 0.09

0.28 ± 0.07*

Posterior cingulate cortex

0.71 ± 0.15

0.39 ± 0.09

0.28 ± 0.07*

Midbrain

1.25 ± 0.30a,b

0.65 ± 0.16a

0.42 ± 0.10*

Pons

1.35 ± 0.37a,b

0.80 ± 0.22a,b,c

0.53 ± 0.15*,a,b,c

Medulla oblongata

1.00 ± 0.24

0.64 ± 0.14a

0.44 ± 0.11*

Cerebral white matter

0.96 ± 0.23

0.68 ± 0.18a

0.51 ± 0.14*,a,b,c

Cerebellar cortex

0.53 ± 0.11

0.31 ± 0.08

0.21 ± 0.05*

Composite†

0.64 ± 0.14

0.36 ± 0.08

0.26 ± 0.06

  1. Data were obtained at 30, 60, and 90 min post-tracer injection (n = 6). Values are the means ± SD. Superscripts * within rows indicate that the mean SUVs differ at 90 min compared with that at 0 min by P < 0.05; a, b, c within columns indicate that the mean SUVs differ from that of the occipital cortex, cerebellar cortex, and temporal cortex by P < 0.05; †Values for the composite comprise the average SUVs for the frontal, parietal, temporal, occipital, anterior cingulate, and posterior cingulate cortices; SUV standardized uptake value