Fig. 4
From: N-acetyl-L-cysteine reduces Leishmania amazonensis-induced inflammation in BALB/c mice
Effect of oral NAC administration on L. amazonensis infected mice on cytokine expression. A significant increase of TNF-α (A), IL-6 (B), and IL-1β (C) levels was detected in paw skin after subcutaneosus infection of L. amazonensis into the mice paw skin. Orally NAC administration (20 mg/kg) significantly reduced levels of all analized cytokines. Values are means ± SEM of five animals for each group. ###P < 0.001 vs. L. amazonensis infected mice; ***P < 0.001 vs. sham