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Table 2 Detection of VSV neutralizing antibodies in goats induced by recombinant adenovirus with VSV-IN at different time points

From: Recombinant adenovirus expressing vesicular stomatitis virus G proteins induce both humoral and cell-mediated immune responses in mice and goats

Group Mean titers over time after first immunizationa
0 weeks 3 weeks 6 weeks 9 weeks 12 weeks
rAd-IN 0 7 (4–8) 28 (16–32) 56 (32–64) 28 (16–32)
rAd-NJ 0 7 (4–8) 14 (8–16) 14 (8–16) 10 (8–16)
rAd-IN-NJ 0 7 (4–8) 14 (8–16) 24 (16–32) 20 (16–32)
wtAd 0 0 0 0 0
PBS 0 0 0 0 0
  1. aMean neutralizing antibody titers at that time point (range of antibody titers). VSV-IN vesicular stomatitis virus-Indiana; rAd-IN recombinant adenovirus-Indiana; rAd-NJ recombinant adenovirus-New Jersey; rAd-IN-NJ recombinant adenovirus-Indiana-New Jersey; wtAd wild-type adenovirus; PBS phosphate-buffered saline