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Table 2 Accession number, peptides, scores, fold-changes and description of the platelet proteomes (n = 10) that were differentially expressed in dogs with congestive heart failure compared to controls. Proteins are listed according to up or down regulation and fold change

From: Platelet proteome changes in dogs with congestive heart failure

Accession no

Peptidesa

P value

Fold change

Protein description

Up or down

P12279

6 (5)

0.04

2,01

Apolipoprotein C-III

Up

P52206

19 (10)

0.02

2,07

Guanine nucleotide-binding protein subunit alpha-11 (Fragment)

Up

E2RAK7

16 (14)

0.03

1,94

Apolipoprotein A-II

Up

P25473

68 (59)

0.03

1,81

Clusterin

Up

Q5KSV9

1 (1)

0.02

2,87

C-X-C motif chemokine 10

Down

P67780

6 (5)

0.02

1,49

Cytochrome C oxidase subunit 2

Down

Q4LAL9

6 (6)

0.04

1,46

Cathepsin D

Down

P05124

51 (45)

0.04

1,28

Creatine kinase B-type

Down

Q8MJ46

13 (6)

0.03

1,24

Serine/threonine-protein phosphatase PP1-gamma catalytic sub.

Down

Q863Z4

19 (16)

0.04

1,20

Myotrophin

Down

  1. a Peptide column shows two values where there first number is the number of identified peptides and the second number in the parentheses is the number of non-conflicting peptides included in intensity calculations
  2. Protein identifications are done against the reviewed Canis lupus familiaris protein database from https://www.uniprot.org/