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Table 3 Liver/kidney function related biomarkers in dairy cows with LDA or healthy cows

From: Potential hemo-biological identification markers to the left displaced abomasum in dairy cows

Detected biomarkers Control LDA p
Mean±SEM 95% CI Mean±SEM 95% CI
ALT (U/L) 19.20±1.42 16.82-21.57 23.20±1.16** 20.82-25.57 0.000
AST (U/L) 86.65±3.18 80.00-93.29 122.87±6.65** 109.27-136.46 0.000
AST/ALT 4.48±0.26 3.92-5.03 6.70±0.35** 5.98-7.42 0.000
GGT (U/L) 23.20±2.56 20.33-25.87 32.07±2.22** 28.52-35.61 0.015
LDH (U/L) 850.37±63.5 744.05-956.68 950.37±51.92* 844.05-1056.68 0.015
TBIL (μmol/L) 4.07±0.5 3.02-5.11 6.30±0.52** 5.23-7.37 0.002
DBIL (μmol/L) 1.54±0.19 1.13-1.95 2.48±0.22** 2.02-2.94 0.001
IBIL (μmol/L) 2.53±0.31 1.87-3.18 3.82±0.34* 3.13-4.51 0.010
TP (g/L) 76.05±1.35 73.23-78.87 68.74±1.81** 65.04-72.43 0.040
ALB (g/L) 33.78±0.66 32.38-35.16 27.35±0.67* 25.98-29.71 0.005
GLO (g/L) 42.27±1.41 39.31-45.22 39.39±1.55 36.21-42.56 0.201
BUN (mmol/L) 4.61±0.3 3.99-5.23 6.20±0.52* 5.14-7.26 0.040
Creatinine (mmol/L) 63.00±2.12 58.55-67.45 79.03±3.4** 72.07-85.99 0.001
  1. The Liver/kidney function related biomarkers of dairy cows with LDA or healthy cows (Control) were shown in the table. Healthy Holstein cows, n = 20; LDA Holstein cows, n = 30. The results are expressed as the mean ± SEM. *P < 0.05, **P < 0.01, compared with respective values in control (healthy) group
  2. ALT Alanine aminotransferase, AST Aspartate aminotransferase, GGT γ glutamyl transpeptidase, LDH Lactate dehydrogenase, TBIL Total bilirubin, DBIL Direct bilirubin, IBIL Indirect bilirubin, TP Total protein, ALB Albumin, GLO Globulin, BUN Blood urea nitrogen