Fig. 3

Distribution of U. diversum antigens in different Brazilian states. The Brazilian states studied are represented in highlighted colors. In each state, the isolated strains and the set of UdLAMPs positive by PCR are used. In bold and underlined are UdLAMPs that (by prediction) showed good characteristics for immunological studies and expression in E. coli, not being retained in any of the exclusion criteria in Diagram 1. Only in bold, the antigens that, although they did not pass all criteria, were maintained in only one or two of the undesirable parameters for use in prophylactic and immunodiagnostic measures in Fig. 1. The figure was acquired at Wikimedia Commons (https://commons.wikimedia.org/wiki/File:Brazil_Map-1.png) and was adapted using Adobe Photoshop CS6 version 13.0.6 × 64