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Table 2 Pharmacokinetic parameters of Ceftiofur after I. M administration (5 mg/kg) in healthy pigs

From: Optimal regimens based on PK/PD cutoff evaluation of ceftiofur against Actinobacillus pleuropneumoniae in swine

Parameters

Units

Healthy

AUC0-24h

μg·h/mL

358.84 ± 91.87

AUC0-∞

μg·h/mL

372.05 ± 97.35

Cmax

μg/mL

22.33 ± 3.17

Tmax

hr

0.66–2

T1/2

h

19.51 ± 2.76

Ke

h-1

0.04 ± 0.01

CL/F

mL/kg/h

282.49 ± 52.91

MRT0-t

h

22.82 ± 1.83

MRT0-∞

h

26.33 ± 2.94

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BMC Veterinary Research

ISSN: 1746-6148

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