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Fig. 2 | BMC Veterinary Research

Fig. 2

From: In-gel digestion coupled with mass spectrometry (GeLC-MS/MS)-based salivary proteomic profiling of canine oral tumors

Fig. 2

Involvement of tyrosine-protein phosphatase non-receptor type 5 (PTPN5) and tumor protein p53 (TP53) in networks of protein chemotherapy drug interactions, cisplatin and doxorubicin, analysed by Stitch, version 5.0; a Interactions of PTPN5 and TP53 with cisplatin; b Interactions of PTPN5 and TP53 with doxorubicin; c Interactions of PTPN5 and TP53 with cyclophosphamide. Red circles: PTPN5 and TP53. Abbreviations: ataxia telangiectasia mutated (ATM), breast cancer 4721, early onset (BRCA1), cyclin-dependent kinase inhibitor 1A (p21, Cip1) (CDKN1A), cyclin-. 34,473 dependent kinase inhibitor 2A (CDKN2A), CREB binding protein (CREBBP), E1A binding 474 protein p300 (EP300), K (lysine) acetyltransferase 2B (KAT2B), mitogen-activated protein kinase 4758 (MAPK8), Mdm2 (MDM2) and sirtuin 1 (SIRT1).

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BMC Veterinary Research

ISSN: 1746-6148

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