Table 1 Liver function and FPP of canines
From: Assessment of a biofluid mechanics-based model for calculating portal pressure in canines
Parameters | Control | CCl4 (1 month) | CCl4 (2 months) | CCl4 (3 months) | CCl4 (4 months) |
|---|---|---|---|---|---|
Total bilirubin (μmol/L) | 2.2 ± 0.9 | 4.6 ± 1.0* | 6.5 ± 0.7* | 5.2 ± 2.5 | 7.3 ± 0.8* |
Direct bilirubin (μmol/L) | 0.5 ± 0.3 | 0.5 ± 2.9 | 2.3 ± 0.3* | 2.3 ± 2.3 | 3.4 ± 1.3* |
Indirect bilirubin (μmol/L) | 1.7 ± 0.7 | 4.0 ± 0.9* | 4.2 ± 0.6* | 3.0 ± 0.3* | 3.9 ± 0.8* |
Alanine aminotransferase (U/L) | 21 ± 8 | 81 ± 47* | 481 ± 178* | 78 ± 46 | 366 ± 110* |
Aspartate transaminase (U/L) | 28 ± 9 | 36 ± 8 | 50 ± 20 | 29 ± 12 | 58 ± 13* |
free portal pressure (mmHg) | 6.6 ± 1.1 | 10.0 ± 1.6* | 13.6 ± 1.5* | 15.6 ± 4.0* | 19.2 ± 1.9* |