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Table 1 Liver function and FPP of canines

From: Assessment of a biofluid mechanics-based model for calculating portal pressure in canines

Parameters Control CCl4
(1 month)
CCl4
(2 months)
CCl4
(3 months)
CCl4
(4 months)
Total bilirubin (μmol/L) 2.2 ± 0.9 4.6 ± 1.0* 6.5 ± 0.7* 5.2 ± 2.5 7.3 ± 0.8*
Direct bilirubin (μmol/L) 0.5 ± 0.3 0.5 ± 2.9 2.3 ± 0.3* 2.3 ± 2.3 3.4 ± 1.3*
Indirect bilirubin (μmol/L) 1.7 ± 0.7 4.0 ± 0.9* 4.2 ± 0.6* 3.0 ± 0.3* 3.9 ± 0.8*
Alanine aminotransferase (U/L) 21 ± 8 81 ± 47* 481 ± 178* 78 ± 46 366 ± 110*
Aspartate transaminase (U/L) 28 ± 9 36 ± 8 50 ± 20 29 ± 12 58 ± 13*
free portal pressure (mmHg) 6.6 ± 1.1 10.0 ± 1.6* 13.6 ± 1.5* 15.6 ± 4.0* 19.2 ± 1.9*
  1. Note. Values are presented as the M ± SD; * meaning P < 0.05 vs. Control group; CCl4 carbon tetrachloride