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Table 5 Swiss prudent use guidelines for cats with aURTDa, FLUTDb and abscesses

From: Antimicrobial prescriptions in cats in Switzerland before and after the introduction of an online antimicrobial stewardship tool

Indication Comment Antibiotic Dosage (mg/kg) Application frequency Treatment duration (days)
aURTDa AMUc is only indicated if poor general condition, fever (≥ 39.5°C), lethargy and/ or anorexia are present. Doxycycline 10 / 5 SIDd/BIDe 5–14
Amoxicillin 15–20 BIDe/TIDf 5–14
FLUTDb AMUc is only indicated in case of UTIg (defined as presence of bacteriuriahin patients with clinical signs of cystitisi);
AMUc is not indicated in patients with indwelling urinary catheters;
Complicated UTIg is defined as infection caused by anatomical or functional changes or disorders of the immune system
Uncomplicated UTIg: Amoxicillin 11–15 BIDe/TIDf 5–7
Complicated UTIg: Amoxicillin/ Clavulanic acid 12.5–20 BIDe/TIDf 5–28
Abscess AMUc is only indicated if signs of generalization (i.e. fever ≥ 39.5°C), poor general condition, severely contaminated wounds, and/or proximity to delicate tissues (e.g. joints, thorax, abdomen, abscesses extending into deep tissue) are present Amoxicillin 15–20 BIDe 5–7
Amoxicillin/ Clavulanic acid 12.5–20 BIDe 5–7
Cefalexin 20–30 BIDe/TIDf 5–7
Clindamycin 10–15 BIDe 5–7
Cefazolin 20 BIDe 5–7
  1. Consistent with the Swiss prudent use guidelines presented in December 2016 as previously published [45], additional details used to faciliate judgement are given in italics; in April 2019 the Swiss prudent use guidelines have been revised; aaURTD, acute upper respiratory tract disease; bFLUTD, feline lower urinary tract diseases; cAMU, antimicrobial use; dSID, once daily; eBID, twice daily; fTID, three times daily; gUTI, urinary tract infection; hPresence of bacteria in the urine sediment analysis or positive bacterial culture results from an aseptically collected urine sample (by cystocentesis or catheterization); iPresence of stranguria, pollakiuria, periuria, pigmenturia or dysuria