Saccharomyces cerevisiae fermentation products (SCFP) stabilize the ruminal microbiota of lactating dairy cows during periods of a depressed rumen pH

Table 3 Relative abundances of rumen microbial domains and phyla affected by Saccharomyces cerevisiae fermentation products (SCFP) supplementation and a subacute ruminal acidosis (SARA) challenge as determined by shotgun metagenomic-based analysis

Item	No SCFP		SCFP		SEM¹		*P-value*
Item	Control	SARA	Control	SARA	SEM¹	SARA	SCFP	SARA *SCFP
Archaea	0.71^y	1.15^x	1.80^x	0.70^y	0.14	0.07	0.07	< 0.01
Euryarchaeota	0.95	1.02	1.69a	0.92b	0.19	0.02	0.02	< 0.01
Bacteria	98.36	97.52	97.05	97.36	0.7	0.72	0.34	0.42
Actinobacteria	3.89	6.76	11.13	6.82	2.15	0.74	0.10	0.11
Bacteroidetes	42.06	36.51	34.59	40.2	4.49	0.99	0.68	0.22
Chlorobi	0	0.03	0	0	0	0.14	0.14	0.14
Fibrobacteres	0.69^a	0.19^b	0.59^a	0.35^b	0.14	0.01	0.82	0.35
Firmicutes	36.9^y	46.49^x	38.25^y	42.01^x	3.78	0.09	0.68	0.45
Fusobacteria	0.02	0	0	0	0.01	0.33	0.33	0.33
Nitrospirae	0.05	0.01	0.02	0	0.02	0.12	0.35	0.75
Planctomycetes	0.14^x	0.05^y	0.2^x	0.11^y	0.04	0.06	0.18	1
Proteobacteria	1.89	1.45	2	1.29	0.35	0.11	0.94	0.7
Spirochaetes	4.67^a	1.52^b	3.52^a	1.86^b	0.64	< 0.01	0.53	0.25
Synergistetes	0.01	0	0	0.01	0.01	1	1	0.18
Tenericutes	5.06^a	2.95^b	4.4^a	2.14^b	0.51	< 0.01	0.16	0.88
Verrucomicrobia	0.16^a	0^b	0.15^b	0.01^b	0.05	< 0.01	1	0.8
Unclassified	1.42	1.31	1.27	2.36	0.37	0.2	0.24	0.12
Eukaryota	0.41	0.4	0.26	1.15	0.46	0.18	0.93	0.16
Chlorophyta	0.04	0.01	0.02	0	0.02	0.21	0.52	1
Streptophyta	0.1	0.14	0.05	0.29	0.1	0.18	0.62	0.33
Unclassified	0.11	0.02	0.41	0.15	0.19	0.37	0.28	0.65

¹SEM standard error of mean
^{a, b}LSmeans with different letters within SCFP treatment (No SCFP or SCFP) differ (P < 0.05)
^{x, y}LSmeans with different letters within SCFP treatment (No SCFP or SCFP) tend to differ (P < 0.10)