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Fig. 8 | BMC Veterinary Research

Fig. 8

From: Inhibiting autophagy potentiates the antitumor efficacy of Euphorbia royleana for canine mammary gland tumors

Fig. 8

E. royleana inhibited the growth of xenograft cMGT. (a) Changes in mouse body weight. (b) X.H.E. inhibited the growth of tumor volumes in vivo. Euthanized CMT1-bearing nude mice after treatment with X.H.E. or vehicle-treated control group. Hematoxylin and eosin–stained tumor tissue slides were photographed. In the vehicle-treated group, (c) saline and (d) DMSO exhibited normal nuclear morphology characterized by diffuse chromatin structures. X.H.E-treated group exhibited (e) necrosis in tumor tissue (arrow) and (f) cell shrinkage, nuclear condensation, increased darkness, and fragmentation. (g) Quantification of necrotic area in tumors. *: p < 0.05; **: p < 0.01

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BMC Veterinary Research

ISSN: 1746-6148

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