Antimicrobial resistance and novel mutations detected in the gyrA and parC genes of Pseudomonas aeruginosa strains isolated from companion dogs

Table 3 Distribution of fluoroquinolone-resistant Pseudomonas aeruginosa from healthy and infected dogs

Antimicrobial agents	MIC (μg/mL)		No. (%) resistant strains		p-value
Antimicrobial agents	Range	Breakpoint	Healthy group (n = 38)	Infected group (n = 46)	p-value
Nalidixic acid	0.05–256	≥32	38 (100.0)	46 (100.0)	n/a
Ciprofloxacin	0.015–32	≥4	4 (10.5)	7 (15.2)	0.747
Levofloxacin	0.015–32	≥8	5 (13.2)	7 (15.2)	0.700
Enrofloxacin	0.03–16	≥4	6 (15.8)	17 (35.4)	0.031 ^a
Marbofloxacin	0.03–16	≥4	5 (13.2)	12 (26.1)	0.142

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