time (min) | 0 | 60 | 120 | 180 | 240 | |||||
---|---|---|---|---|---|---|---|---|---|---|
median (range) | P | median (range) | P | median (range) | P | median (range) | P | median (range) | P | |
HCO3- a (mmol/L) | 22.8 (19.3–24.5) | 0.003 | 21.1 (20.3–25) | 0.011 | 22.7 (19.7–25.5) | 0.023 | 22.6 (20.7–25.2) | 0.033 | 22.2 (19.9–27.1) | |
HCO3- v (mmol/L) | 23.6 (21.4–24.7) | 24.2 (21–25.1) | 23.5 (21.4–26.6) | 22.4 (22.3–26.4) | 22.9 (21.4–29.9) | |||||
BE a (mmol/L) | −2.3 (−7.6--0.9) | <0.001 | −3.9 (−8.3--2.3) | −3.5 (−9.3--2) | −5 (−6.1--0.8) | −2.7 (−8.2–0.1) | ||||
BE v (mmol/L) | −5.3 (−7.4--4.4) | −3.8 (−8.4--2.9) | −4.4 (−9--1.6) | −4.9 (− 7.5--2.2) | − 5.1 (− 7.3--1.3) | |||||
Na + a (mmol/L) | 135.3 (132–138.8) | 0.001 | 138.9 (132.6–140.5) | <0.001 | 139 (131.6–141.7) | <0.001 | 140.65 (135.1–152) | 0.002 | 138 (137.2–146) | 0.001 |
Na + v (mmol/L) | 140.6 (134.8–144) | 143.5 (138.7–144.3) | 143.6 (138.7–148.2) | 145.8 (137.2–154) | 146.5 (140–152) | |||||
K+ a (mmol/L) | 5.76 (4.66–6.8) | 5.61 (4.91–6.43) | 5.73 (4.46–6.19) | 5.62 (4.47–6.95) | 5.86 (4.71–6.89) | 0.049 | ||||
K+ v (mmol/L) | 6.43 (5.05–9.6) | 5.49 (4.46–7.09) | 5.54 (4.46–6.55) | 5.76 (4.66–7.18) | 6.6 (4.91–7.6) | |||||
Ca2+ a (mmol/L) | 1.48 (1.4–1.62) | 1.52 (1.41–1.59) | 1.5 (1.41–1.62) | 0.03 | 1.53 (1.43–1.63) | 0.017 | 1.53 (1.44–1.68) | 0.012 | ||
Ca2+ v (mmol/L) | 1.49 (1.42–1.59) | 1.51 (1.44–1.61) | 1.53 (1.44–1.63) | 1.55 (1.47–1.63) | 1.56 (1.46–1.68) | |||||
Cl- a (mmol/L) | 105.8 (102.2–108.8) | 0.001 | 107.2 (101.7–110.3) | 0.001 | 109.4 (101.6–114) | 107.6 (101.3–113) | 0.006 | 107.6 (101.9–111.5) | 0.003 | |
Cl- v (mmol/L) | 110.4 (106.5–114.2) | 109.3 (102.6–112.6) | 109.9 (101.8–113.8) | 111.1 (102.1–114.1) | 110.9 (101.5–113.2) | |||||
glucose a (mmol/L) | 85 (76–105) | 0.005 | 116 (93–141) | <0.001 | 112 (95–187) | 0.002 | 121 (85–190) | 0.019 | 105 (92–176) | 0.026 |
glucose v (mmol/L) | 162 (126–339) | 136 (117–178) | 142 (111–208) | 145 (107–219) | 121 (100–201) |