Assessment of Leishmania infantum infection in equine populations in a canine visceral leishmaniosis transmission area

Table 4 Biochemical profile in control group and Leishmania infantum infected equines and canines

	Control Group	Infected Group	p- value	Control Group	Infected Group	p- value
	(X±SD)	(X±SD)		(X±SD)	(X±SD)
	Equine Samples			Canine Samples
AST (Ul/L)	243.60 ± 129.49	218.64 ± 46.41	0.55^b	7.83 ± 3.86	12.71 ± 9.19	0.28^a
GGT (Ul/L)	20.77 ± 12.49	15.91 ± 4.94	0.30 ^b	5.57 ± 2.07	6.17 ± 3.06	0.68 ^a
Creatinine (mg/dL)	1.20 ± 0.26	1.22 ± 0.31	0.96 ^b	1.14 ± 0.25	1.15 ± 0.53	0.95 ^a
Urea (mg/dL)	48.31 ± 11.46	57.52 ± 13.61	0.01^a*	24.00 ± 2.12	28.04 ± 19.90	0.96 ^a
Total Protein (g/dl)	9.82 ± 0.99	9.35 ± 0.97	0.14 ^a	6.55 ± 0.94	7.16 ± 0.99	0.22 ^a
CK (Ul/L)	387.85 ± 212.38	365.91 ± 171.44	0.87 ^b	-	-
ALB (g/dl)	4.08 ± 0.49	4.06 ± 0.50	0.91^a	2.55 ± 0.50	2.27 ± 0.37	0.23 ^a
Globulin (g/dl)	5.73 ± 1.21	5.29 ± 1.16	0.28 ^b	3.99 ± 1.31	4.98 ± 1.29	0.16 ^a
Gamma Globulin	18.81 ± 3.81	19.35 ± 4.89	0.67 ^a	1.15 ± 0.41	1.61 ± 0.92	0.31^a
A/G	0.75 ± 0.22	0.63 ± 0.22	0.29 ^a	0.75 ± 0.42	0.49 ± 0.18	0.17 ^a

X Mean, SD Standard Deviation; *The difference was considered significant when P value less than 0.05; ^a Student T test; ^b Wilcoxon test. Reference values for equine specie; AST: 120-480; GGT: 10-62; Creatinine: 0.96-1.3; Urea: 21.6-51; Total Protein: 5.8-8.7; CK: 40-280; ALB: 2.6 – 3.8; Globulin: 2.5 – 4.1; Gglobulin: No reference values were found in the literature. A/G: 0.5-1.7; Reference values for canine specie: AST: 23-66; GGT: 1.2-6.4; Creatinine: 0.5-1.5; Urea: 15-65; Total Protein: 5.4-7.1; ALB: 2.6 – 3.3; Globulin: 2.5 – 4.1; Gglobulin: 0.8-1.8; A/G: 0.5-1.7