Table 7 Clinical trials carried out with mesenchymal stem cells in canine and feline inflammatory bowel disease
From: Mesenchymal stem cells therapy in companion animals: useful for immune-mediated diseases?
Specie (number) | Treatment | Results | Conclusion | Reference |
|---|---|---|---|---|
Dog (11) | Single IV allogeneic ASCs (2 × 106 cells/kg) | After 2 weeks of MSCs therapy, a clinical response occurred in all dogs | ASCs was well tolerated and appeared to produce clinical benefits in dogs and cats with IBD | [67] |
Cat (7) | Two IV allogeneic ASCs (2 × 106 cells/kg) | Improved clinical signs in 5/7 MSCs-treated cats | [69] |