Table 3 Insulin concentrations (geometric mean, 95% CI) measured during a combined-insulin-glucose tolerance test in control and velagliflozin (treated) ponies
Wk-0 | Wk-16 | Wk-21 | |
|---|---|---|---|
Insulin 0 min, μIU/mL | |||
Control, n = 10 | 5.4 (3.1 – 9.4) | 5.8 (3.9 – 8.6) | 8.7 (5.8 – 13.1) |
Treated, n = 12 | 6.4 (2.7 – 15.3) | 4.9 (3.4 – 7.1) | 6.7 (4.6 – 9.6) |
Insulin 45 min, μIU/mL | |||
Control, n = 10 | 73.5 (40.7 – 132.8) | 61.5 (41.5 – 91.2) | 73.2 (46.5 – 115.4) |
Treated, n = 12 | 95.4 (52.9 – 172.1) | 96.2 (54.0 – 171.4) | 83.0 (55.6 – 123.8) |
Insulin 75 min, μIU/mL | |||
Control, n = 10 | 27.7 (16.7 – 46.1) | 21.1 (12.3 – 36.0) | 20.9 (10.5 – 41.5) |
Treated, n = 12 | 33.1 (18.3 – 59.8) | 28.9 (16.2 – 51.5) | 26.4 (15.0 – 46.5) |
Number insulin resistant† | |||
Control, n = 10 | 4/10 (40%) | 3/10 (30%) | 2/10 (20%) |
Treated, n = 12 | 5/12 (42%) | 5/12 (42%) | 5/12 (42%) |