Table 2 Distribution of PrPCWD deposits in peripheral nerves, glands and organs of clinically affected and non-inoculated white-tailed deer
| Â | Non-inoculated | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
wt/wt | ||||||||||||
Genotype | wt/wt | S96/wt | H95/wt | H95/S96 | ||||||||
D1 | D2 | D3 | D4 | D5 | D6 | D7 | D8 | D9 | D10 | D11 | D12 | |
Optic nerve | ++ | + | ++ | + | + | + | / | + | + | ++ | / | – |
Vagus nerve | ++ | + | + | / | / | + | – | + | – | + | – | – |
Brachial plexus | / | – | – | / | / | – | – | / | / | – | – | – |
Sciatic nerve | + | + | – | / | – | – | / | – | – | – | – | – |
Pituitary gland | / | ++ | +++ | / | / | +++ | +++ | +++ | / | +++ | – | – |
Islets of Langerhans | ++ | ++ | ++ | ++ | ++ | ++ | + | + | – | – | / | – |
Adrenal Gl medulla | +++ | +++ | +++ | +++ | ++ | +++ | +++ | +++ | + | ++ | / | – |
Ileoc. Valve villi/crypts | ++ | + | + | + | ++ | ++ | ++ | / | – | – | – | – |
Kidney | ++a | + | + | + | + | / | + | + | – | – | – | – |
Parotid salivary gland | + | + | – | / | + | + | – | + | – | / | / | – |
Submandibular sal. Gl | / | + | – | / | + | + | + | + | – | – | / | – |
Sublingual sal. Gl | / | – | – | / | / | – | – | – | – | – | / | – |
Retina | +++ | +++ | +++ | + | +++ | +++ | + | +++ | ++ | ++ | / | – |
Skeletal muscle | – | – | – | – | – | – | – | – | – | – | – | – |
Heart | / | / | / | / | / | ++ | / | / | – | – | / | / |
Lung | + a | – | – | – | – | – | – | – | – | – | – | – |
Liver | – | – | – | – | – | – | – | – | – | – | – | – |