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Fig. 4 | BMC Veterinary Research

Fig. 4

From: Deletion of the ORF2 gene of the neuropathogenic equine herpesvirus type 1 strain Ab4 reduces virulence while maintaining strong immunogenicity

Fig. 4

Anti-EHV-1 gC antibodies in serum after EHV-1 infection. Three groups of horses (n = 8/group) were either not infected (control), infected with the neuropathogenic EHV-1 strain Ab4 (Ab4) or infected with its ORF2 deletion mutant (Ab4ΔORF2) on day 0 (arrow). Before (day − 1) and after (day 1–260). EHV-1 gC specific total Ig (a), IgG1 (b), IgG1/3 (c), IgG4/7 (d), IgG3/5 (e) and IgG6 (f) were quantified in serum by fluorescent bead-based multiplex assays and expressed as median fluorescent intensities (MFI). Note that Y-axes scales differ depending on isotype. Mean and standard errors are plotted for each group. Significant differences between groups are marked: a = Ab4 vs. control, b = Ab4ΔORF2 vs. control, c = Ab4 vs. Ab4ΔORF2

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BMC Veterinary Research

ISSN: 1746-6148

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