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Table 2 Results of the clinical parameters, macroscopic and microscopic lung lesions in the different experimental groups

From: Clinical impact of deoxynivalenol, 3-acetyl-deoxynivalenol and 15-acetyl-deoxynivalenol on the severity of an experimental Mycoplasma hyopneumoniae infection in pigs

Parameter Groups
  NCG (n = 5) DON (n = 15) DONMHYO (n = 15) MHYO (n = 15) P-value
RDS
 D1–7 0 ± 0 0 ± 0 0 ± 0 0 ± 0 1.00
 D8–35 0 ± 0a 0.01 ± 0.03a 1.04 ± 0.82b 1.14 ± 0.92b < 0.001
 D1–35 0 ± 0a 0.01 ± 0.03a 0.83 ± 0.84b 0.91 ± 0.94b < 0.001
Weight ± SD (kg)
 D0 6.37 ± 1.09 6.39 ± 0.92 6.38 ± 1.04 6.42 ± 1.23 1.00
 D8 7.70 ± 1.13 8.04 ± 1.27 8.20 ± 1.08 8.11 ± 1.90 0.92
 D35/36 20.10 ± 2.33 19.45 ± 3.83 21.02 ± 3.18 21.75 ± 4.36 0.38
ADG (kg/pig/day)
 D0–8 0.52 ± 0.14 0.53 ± 0.19 0.56 ± 0.15 0.67 ± 0.17 0.12
 D0–35/36 0.39 ± 0.06 0.37 ± 0.11 0.41 ± 0.08 0.43 ± 0.10 0.41
 D8–35/36 0.46 ± 0.08 0.42 ± 0.13 0.46 ± 0.10 0.49 ± 0.10 0.37
MLL, histopathology and percentage of air D35/36
 MLL 0 ± 0a 0 ± 0a 2.77 ± 3.22b 5.87 ± 7.32b < 0.001
 Histopathology 1.70 ± 0.20a 2.00 ± 0.30a 2.40 ± 0.80b 2.40 ± 0.90b < 0.001
 Percentage of air (%) 45.94 ± 6.54 46.85 ± 6.86 49.75 ± 9.90 46.96 ± 8.51 0.25
  1. Respiratory disease score (RDS), bodyweight, average daily weight gain (ADG), macroscopic lung lesions (MLL), histopathology score of the lungs and percentage of air in the lungs for NCG, DON group, DONMHYO group, MHYO group
  2. The parameters bodyweight, ADG, percentage of air analysis were analysed by means of one way analysis of variance, the parameter RDS with a repeated measures analysis of variance, in both cases with Scheffé post-hoc test to make pair-wised comparisons, therefore means ± SD are reported. The parameter MLL and histopathology were analysed with Kruskal-Wallis test and the Dunn-Bonferroni approach to make pair-wised comparison, therefore medians and interquartile range are reported. Different superscripts in one row are statistically different (P < 0.05)
  3. NCG: negative control group, DON: deoxynivalenol contaminated group, DONMHYO: deoxynivalenol contaminated +M. hyopneumoniae-inoculated group, MHYO: M. hyopneumoniae-inoculated group, SD: standard deviation, n number, D Day of the study, ADG average daily gain, RDS respiratory disease score, MLL macroscopic lung lesions