Table 3 The differences of the potential antigenic peptide in gB, gC and gD between Qihe547 and Bartha ADV. In the N terminus of ADV gB, there are antigenically important regions, such as (AA59-AA126, AA214-AA279, AA507-AA734) [21]. The extracellular region (AA23-AA453) of ADV gC plays an important role in ADV adsorption, neutralizing antibody generation and virus neutralization. gD also is the main target of ADV antibody. Mutation occurred in these regions may result antigen drift. Numerous AA mutations and potential antigenic peptides differences were found in gB, gC and gD of Qihe547, this may lead to immune failure

From: Genetic characterization and mutation analysis of Qihe547 Aujeszky’s disease virus in China