Safety studies with the oral rabies virus vaccine strain SPBN GASGAS in the small Indian mongoose (Herpestes auropunctatus)

Table 1 Overview of safety studies conducted in the small Indian mongoose

Purpose	Number of animals	Observation period (days)	Dose (titre; volume)
Repeated dose (day 0, 3 & 7)	5	56	10^7.7 FFU/ml; 0.7 ml
Dissemination	12	1, 2, 3, 5, 7 & 10	10^7.7 FFU/ml; 0.7 ml
Overdose	14	182	10^9.1 FFU/ml; 0.7 ml
Different routes of administration	5 (i.m.)	15, 20, 25, 30 & 35	10^7.7 FFU/ml; 1.0 ml
	5 (d.o.a)	15, 20, 25, 30 & 35	10^7.7 FFU/ml; 1.0 ml
	5 (i.c.)	3, 6, 9, 15 & 30	10^7.7 FFU/ml; 0.1 ml

ISSN: 1746-6148