Thromboelastometric assessment of hemostasis following hydroxyethyl starch (130/0.4) administration as a constant rate infusion in hypoalbuminemic dogs

Table 3 ROTEM results at baseline (N = 20)

T0	In-TEM®				Ex-TEM®				Fib-TEM®
G 1 (N = 11)	CT	CFT	MCF	α angle	CT	CFT	MCF	α angle	CT	MCF	α angle	MCE platelet	Fib	Disease
Dog 1	216	85	72	73	43	56	80	80	107	38	73	339	3.2	APLE
Dog 2	132	104	75	73	43	159	64	61	56	119	25	144	3.5	APLE
Dog 3	142	54	70	79	39	67	69	76	45	11	70	210	3.2	CPLE
Dog 4	144	52	70	80	27	74	67	75	31	13	73	188	2.7	CPLE
Dog 5	180	132	56	65	61	143	60	62	51	7	ND	142	3.5	APLE
Dog 6	180	45	75	81	41	38	79	83	38	34	86	325	6.2	PLN
Dog 7	156	47	80	80	53	66	81	79	50	28	83	387	6	CPLE
Dog 8	163	63	75	77	44	83	77	75	41	16	78	316	4.4	CH
Dog 9	241	50	79	80	61	47	82	81	54	34	79	404	8.5	CH
Dog 10	268	103	62	69	48	107	68	74	47	14	77	196	3.3	CPLE
Dog 11	184	66	70	76	46	60	77	78	37	29	80	294	5.3	APLE
G 2 (N = 9)
Dog 12	241	52	77	79	46	51	82	80	45	30	80	383	7.4	CPLE
Dog 13	279	86	68	73	48	82	69	73	46	14	67	206	2.2	CPLE
Dog 14	198	79	67	74	40	96	67	71	36	22	79	175	4.2	CPLE
Dog 15	196	51	71	79	43	60	73	78	46	15	76	253	2.7	CPLE
Dog 16	119	41	72	82	30	57	75	79	29	30	81	257	4.6	CH
Dog 17	188	73	67	75	59	89	69	73	60	15	75	205	3.5	CH
Dog 18	151	75	64	76	38	72	70	75	38	22	77	205	2.8	CPLE
Dog 19	112	57	73	78	56	81	73	74	31	9	ND	260	2.4	AD
Dog 20	133	80	62	74	89	86	66	73	92	14	69	178	3.4	CPLE

G 1 Group 1 (1 ml/kg/h), G 2 Group 2 (2 ml/kg /h), In-TEM® intrinsic thromboelastometry pathway, Ex-TEM® extrinsic thromboelastometry pathway, Fib-TEM® functional fibrinogen, CT clotting time (s), CFT clot formation time (s), MCF maximum clot firmness (mm), MCE_platelet platelets contribution to clot elasticity, Fib fibrinogen level (g/L), AD hypoadrenocorticism, APLE acute protein losing enteropathy, CH chylothorax, PLN protein losing nephropathy, CPLE protein losing enteropathy, ND not determined, italicize numbers indicate the hypercoagulable dogs at T0 (N=7) and are outside the institutional reference ranges. Institutional reference ranges: In-TEM® (CT, 126–363 s; CFT, 47–224 s; MCF, 50–75 mm; α angle, 55–81°), Ex-TEM® (CT, 29–92 s; CFT, 54–275 s; MCF, 36–73; α angle, 47–79°), Fib-TEM® (CT, 14–102 s; MCF, 6–26; α angle, 40–78°)¹⁴ and fibrinogen level (1.5–4.50 g/L)

ISSN: 1746-6148