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Table 3 Plasma pharmacokinetic parameters (means ± SD) of danofloxacin after i.m. administration at a dosage of 1.25 mg/kg in the three experimental groups; n = 6

From: Flaxseed-enriched diets change milk concentration of the antimicrobial danofloxacin in sheep

Parameter Control Flaxseed 10% Flaxseed 15%
AUC 0–24, μg·h/mL 1.74 ± 0.37 1.92 ± 0.26 1.79 ± 0.15
AUC 0-∞, μg·h/mL 1.75 ± 0.38 1.93 ± 0.25 1.81 ± 0.15
Cmax, μg/mL 0.31 ± 0.05 0.31 ± 0.06 0.30 ± 0.04
MRT, h 4.22 ± 0.73 4.77 ± 0.49 4.95 ± 0.39
Tmax, h 1.50 ± 0.50 1.50 ± 0.50 1.16 ± 0.37