Table 3 Plasma pharmacokinetic parameters (means ± SD) of danofloxacin after i.m. administration at a dosage of 1.25 mg/kg in the three experimental groups; n = 6
From: Flaxseed-enriched diets change milk concentration of the antimicrobial danofloxacin in sheep
Parameter | Control | Flaxseed 10% | Flaxseed 15% |
|---|---|---|---|
AUC 0–24, μg·h/mL | 1.74 ± 0.37 | 1.92 ± 0.26 | 1.79 ± 0.15 |
AUC 0-∞, μg·h/mL | 1.75 ± 0.38 | 1.93 ± 0.25 | 1.81 ± 0.15 |
Cmax, μg/mL | 0.31 ± 0.05 | 0.31 ± 0.06 | 0.30 ± 0.04 |
MRT, h | 4.22 ± 0.73 | 4.77 ± 0.49 | 4.95 ± 0.39 |
Tmax, h | 1.50 ± 0.50 | 1.50 ± 0.50 | 1.16 ± 0.37 |