Table 1 The most over-represented KEGG pathways for each miRNA based on a predicted target gene list
miRNA | Fold change | adjusted P value | n genes | Top KEGG pathway | P value |
|---|---|---|---|---|---|
hsa-let-7d-3p | −0.68 | 0.002 | 3 | NA | NA |
hsa-miR-21-5p | 0.92 | 0.002 | 243 | Cytokine-cytokine receptor interaction | 2.48E-06 |
hsa-let-7d-5p | −0.44 | 0.022 | 370 | ECM-receptor interaction | 9.22E-06 |
hsa-miR-30b-5p | 0.52 | 0.023 | 1113 | Ubiquitin mediated proteolysis | 4.76E-10 |
hsa-miR-30e-5p | 0.64 | 0.042 | 1153 | Ubiquitin mediated proteolysis | 2.92E-08 |