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Table 3 Correlation of serum gastrin with variables of the histologic score for canine CE

From: Effect of gastric acid-suppressive therapy and biological variation of serum gastrin concentrations in dogs with chronic enteropathies

Histologic findings correlated with   serum gastrin concentration (ng/L)
  N Spearman ρ unadjusted P adjusted P #
Stomach (composite score) 97 −0.1291 0.2075 0.4150
Fundus: Morphologic criteria (sum) 92 0.0885 0.4014 ns
- Surface epithelial injury 92 0.0517 0.6248 ns
- Gastric pit epithelial injury 92 0.0151 0.8866 ns
- Mucosal fibrosis 92 0.0167 0.8741 ns
Fundus: Inflammatory criteria (sum) 92 −0.0902 0.3923 ns
- Intraepithelial lymphocytes 92 −0.0434 0.6815 ns
- Lamina propria LPC 92 −0.1358 0.1966 ns
- Lamina propria eosinophils 92 0.0408 0.6993 ns
- Lamina propria neutrophils 92 −0.0938 0.3740 ns
- Lamina propria macrophages 92 −0.0938 0.3740 ns
- Lymphoid follicular hyperplasia 92 0.0079 0.9401 ns
Antrum: Morphologic criteria (sum) 86 0.0299 0.7844 ns
- Surface epithelial injury 86 0.3241 0.0023 0.0069
- Gastric pit epithelial injury 86 −0.1258 0.2483 ns
- Mucosal fibrosis 86 −0.0968 0.3754 ns
Antrum: Inflammatory criteria (sum) 86 −0.1489 0.1737 0.6948
- Intraepithelial lymphocytes 86 −0.0474 0.6650 ns
- Lamina propria LPC 86 −0.1969 0.0691 0.4146
- Lamina propria eosinophils 86 0.0140 0.8990 ns
- Lamina propria neutrophils 86 −0.1933 0.0745 0.4470
- Lamina propria macrophages 86 −0.0651 0.5512 ns
- Lymphoid follicular hyperplasia 86 −0.0815 0.4557 ns
Duodenum (composite score) 100 0.2108 0.0362 0.0724
Morphologic criteria (sum) 100 0.1178 0.2432 0.4864
- Villus stunting 100 0.1130 0.2629 ns
- Epithelial injury 100 0.0452 0.6554 ns
- Crypt distension 100 0.0966 0.3391 ns
- Lacteal dilation 100 0.1320 0.1906 0.9530
- Mucosal fibrosis 100 −0.0467 0.6444 ns
Inflammatory criteria (sum) 100 0.1239 0.2218 0.4436
- Intraepithelial lymphocytes 100 −0.0877 0.3855 ns
- Lamina propria LPC 100 0.0680 0.5013 ns
- Lamina propria eosinophils 100 0.1927 0.0560 0.2800
- Lamina propria neutrophils 100 0.1096 0.2779 ns
- Lamina propria macrophages 100 0.0663 0.5121 ns
  1. Relationship between serum gastrin concentrations and the severity of morphologic and inflammatory histologic lesions of the stomach and duodenum in dogs with CE (n = 102)
  2. CE chronic enteropathy, LPC lymphocytes/plasma cells, N sample size, ns non-significant with P = 1.0000; without correction (P < 0.05); #after Holm-Bonferroni correction (n = 2, 4, or 5)
  3. P values in boldface and italicized indicate significance at P < 0.05