From: Sponsorship bias and quality of randomised controlled trials in veterinary medicine
Risk of bias | Pharmaceutical funding/involvement (86 trials) | Non pharmaceutical funding declared (19 trials) | No funding source declared (21 trials) | All trials (126 trials) | |
---|---|---|---|---|---|
Sequence generation | High | 3 (3.5%) | 0 (0%) | 0 (0%) | 3 (2.4%) |
Low | 16 (18.6%) | 7 (36.8%) | 8 (38.1%) | 31 (24.6%) | |
Unclear | 67 (77.9%) | 12 (63.2%) | 13 (61.9%) | 92 (73.0%) | |
Allocation concealment | High | 5 (5.8%) | 1 (5.3%) | 0 (0%) | 6 (4.8%) |
Low | 5 (5.8%) | 3 (15.8%) | 3 (14.3%) | 11 (8.7%) | |
Unclear | 76 (88.4%) | 15 (78.9%) | 18 (85.7%) | 109 (86.5%) | |
Blinding | High | 5 (5.8%) | 3 (15.8%) | 2 (9.5%) | 10 (7.9%) |
Low | 29 (33.7%) | 7 (36.8%) | 8 (38.1%) | 44 (34.9%) | |
Unclear | 52 (60.5%) | 9 (47.4%) | 11 (52.4%) | 72 (57.1%) | |
Incomplete outcome reporting | High | 14 (16.3%) | 1 (5.3%) | 4 (19.0%) | 19 (15.1%) |
Low | 36 (41.9%) | 15 (78.9%) | 14 (66.7%) | 65 (51.6%) | |
Unclear | 36 (41.9%) | 3 (15.8%) | 3 (14.3%) | 42 (33.3%) | |
Selective outcome reporting | High | 18 (20.9%) | 5 (26.3%) | 6 (28.6%) | 29 (23.0%) |
Low | 64 (74.4%) | 11 (57.9%) | 12 (57.1%) | 87 (69.0%) | |
Unclear | 4 (4.7%) | 3 (15.8%) | 3 (14.3%) | 10 (7.9%) |