Table 4 Mean and 95% posterior credible intervals (PCI) for the sensitivity (Se) and specificity (Sp) of two serum ELISAs and one fecal qPCR, depending on different scenarios
Dataset | Mean (95% PCI) | ||
|---|---|---|---|
Se | Sp | ||
Doubtful ELISA results as negative, fecal qPCR cut-off Ct ≤ 42 | ELISA A | 17.3 (11.0; 24.8) | 95.3 (93.7; 96.7) |
ELISA B | 14.7 (8.5; 22.4) | 95.6 (94.0; 97.0) | |
Fecal qPCR | 50.9 (31.3; 73.3) | 99.2 (98.2; 99.8) | |
Doubtful ELISA results as positive, fecal qPCR cut-off Ct ≤ 40 | ELISA A | 21.0 (12.8; 30.8) | 94.8 (93.1; 96.3) |
ELISA B | 20.0 (11.9; 30.2) | 94.0 (92.2; 95.6) | |
Fecal qPCR | 40.7 (23.5; 63.2) | 99.0 (98.0; 99.7) | |
Doubtful ELISA results as negative, fecal qPCR cut-off Ct ≤ 40 | ELISA A | 21.2 (12.9; 31.0) | 95.3 (93.7; 96.7) |
ELISA B | 17.4 (9.5; 27.5) | 95.5 (94.0; 96.9) | |
Fecal qPCR | 45.8 (26.2; 69.3) | 99.2 (98.2; 99.8) | |