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Table 3 PK/PD analysis of marbofloxacin in TCF infection model

From: Integrated pharmacokinetic–Pharmacodynamic (PK/PD) model to evaluate the in vivo antimicrobial activity of Marbofloxacin against Pasteurella multocida in piglets

Parameter(unit)

Value

Emax (log10(CFU/mL))

0.05

E0(log10(CFU/mL))

−4.20

AUC24/MIC for 1log reduction(h)

13.48

AUC24/MIC EC50(h)

29.78

AUC24/MIC for bactericidal action(h)

57.70

Slope(N)

1.41

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BMC Veterinary Research

ISSN: 1746-6148

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