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Table 1 AUC24 and Cmax of marbofloxacin following multiple dosages in the P. multocida infected tissue cage fluid

From: Integrated pharmacokinetic–Pharmacodynamic (PK/PD) model to evaluate the in vivo antimicrobial activity of Marbofloxacin against Pasteurella multocida in piglets

Doses(mg/kg)

AUC24(h·μg/mL) (Xa ± SD)

Cmax(μg/mL) (Xa ± SD)

0.15

0.72 ± 0.09

0.04 ± 0.01

0.3

2.04 ± 0.23

0.11 ± 0.01

0.5

2.70 ± 0.20

0.14 ± 0.01

0.8

4.65 ± 0.68

0.27 ± 0.07

1.0

5.25 ± 0.40

0.31 ± 0.07

1.3

7.89 ± 1.49

0.51 ± 0.06

1.6

8.53 ± 0.70

0.53 ± 0.06

2.0

9.70 ± 0.82

0.54 ± 0.12

2.5

12.03 ± 0.56

0.74 ± 0.10

  1. Xa is the mean value.
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BMC Veterinary Research

ISSN: 1746-6148

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