Safety pharmacology and subchronic toxicity of jinqing granules in rats

BMC Veterinary Research

Table 2 The effects of Jinqing granules on the heart rate of rats (n = 10)

Jinqing dose	Gender	Before dosing	The second day after dosing	One week after dosing
Control group	Male	333.60 ± 25.96	372.40 ± 27.17	397.00 ± 36.92
Control group	Female	387.60 ± 10.21	358.80 ± 70.38	406.40 ± 12.90
2 g/kg	Male	328.20 ± 23.30	369.40 ± 48.82	396.20 ± 10.64
2 g/kg	Female	392.20 ± 9.39	420.40 ± 25.31	342.60 ± 24.33
4 g/kg	Male	330.20 ± 28.96	336.40 ± 38.40	369.20 ± 57.80
4 g/kg	Female	389.20 ± 11.61	324.00 ± 16.55	382.20 ± 49.47
8 g/kg	Male	333.60 ± 25.96	308.60 ± 35.81	388.60 ± 35.41
8 g/kg	Female	387.60 ± 10.21	341.60 ± 48.69	362.00 ± 41.41
16 g/kg	Male	334.50 ± 21.89	371.25 ± 27.37	388.50 ± 13.96
16 g/kg	Female	372.25 ± 10.84	403.25 ± 74.22	367.25 ± 34.88

Values represent means ± SD (N = 10). P values for all comparisons of before dosing and after dosing were ≥0.05

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