Skip to main content

Table 4 Integration of PK/PD parameters of sarafloxacin against E. coli O78 after i.v. and p.o. administration (10 mg/kg) in ducks

From: Pharmacokinetic and pharmacodynamic modeling of sarafloxacin against avian pathogenic Escherichia coli in Muscovy ducks

Parameter IV PO
AUC0-24 h/MIC (h) 34.3 ± 4.72 33.5 ± 4.44
Cmax/MIC - 8.12 ± 2.92
AUC0-24 h/MBC (h) 17.2 ± 2.36 16.7 ± 2.23
Cmax/MBC - 4.06 ± 1.45
AUC0-24 h/MPC (h) 8.57 ± 1.18 8.37 ± 1.11
Cmax/MPC - 2.03 ± 0.73