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Table 4 Integration of PK/PD parameters of sarafloxacin against E. coli O78 after i.v. and p.o. administration (10 mg/kg) in ducks

From: Pharmacokinetic and pharmacodynamic modeling of sarafloxacin against avian pathogenic Escherichia coli in Muscovy ducks

Parameter

IV

PO

AUC0-24 h/MIC (h)

34.3 ± 4.72

33.5 ± 4.44

Cmax/MIC

-

8.12 ± 2.92

AUC0-24 h/MBC (h)

17.2 ± 2.36

16.7 ± 2.23

Cmax/MBC

-

4.06 ± 1.45

AUC0-24 h/MPC (h)

8.57 ± 1.18

8.37 ± 1.11

Cmax/MPC

-

2.03 ± 0.73

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BMC Veterinary Research

ISSN: 1746-6148

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