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Table 3 Complete blood count, serum chemistry, and urinary values (mean ± SD) and range for eight beagles dogs included in the study at different time points

From: Food-specific sublingual immunotherapy is well tolerated and safe in healthy dogs: a blind, randomized, placebo-controlled study

Parameters

Mean ± SD

Range

Day 0

Day 70

Day 119

P

T

P

T

P

T

Complete blood count values

 RBC

6,97 ± 0,72

6,39 ± 0,23

-

-

7,39 ± 0,88

6,94 ± 0,04

6,20–8,70 milj/μl

 Haematocrit

47,8 ± 5,56

44,33 ± 1,99

-

-

47,45 ± 8,04

46,03 ± 1,66

43,0–59,0%

 Haemoglobin

16 ± 2,21

14,88 ± 0,25

-

-

16,68 ± 2,09

15,98 ± 0,49

14,0–20,0 g/dl

 MCV

68,57 ± 1,96

69,38 ± 2,23

-

-

63,95 ± 4,09

66,33 ± 2,12

63,0–77,0 fl

 MCHC

33,37 ± 0,78

33,58 ± 1,55

-

-

35,4 ± 2,05

34,7 ± 0,56

30,0–36,0 g/dl

 %Reticulocyte

0,43 ± 0,15

0,35 ± 0,19

-

-

0,78 ± 0,55

0,55 ± 0,33

2-0%

 WBC

7556,67 ± 2091,28

7157,5 ± 1088,8

-

-

6815 ± 2775,81

8180 ± 1047

6000–16000 /μl

 Neutrophil

66,23 ± 7,83

68,68 ± 1,41

-

-

62,88 ± 10,23

64,88 ± 4,84

55,0–77,0%

 Lymphocyte

25,67 ± 6,13

20,98 ± 3,38

-

-

22,23 ± 2,88

19,53 ± 2,31

12,0–35,0%

 Monocyte

4,2 ± 0,75

4,23 ± 0,59

-

-

6,75 ± 1,62

8,05 ± 1,23

0,0–10,0%

 Eosinophil

3,17 ± 2,67

5,88 ± 3,52

-

-

7,98 ± 13,04

7,28 ± 3,36

0,0–8,0%

 Basophil

0,7 ± 0,26

0,15 ± 0,1

-

-

0,18 ± 0,17

0,28 ± 0,15

0–1%

 Platelet

395666,67 ± 137587,55

321500 ± 80172,73

-

-

310500 ± 63321,93

248500 ± 29949,96

164000–510000

Biochemical values

 Urea

2,35 ± 0,68

2,45 ± 1,05

3,2 ± 1,10

3,55 ± 1,95

2,7 ± 0,42

3,1 ± 1,70

2,5–9,6 mmol/L

 Crea

28,5 ± 14,18

23,5 ± 8,54

32 ± 11,78

26 ± 9,80

24,5 ± 7,19

32 ± 28

44–159 mmol/L

 ALT

24 ± 4,90

26,5 ± 5,26

33,5 ± 8,22

35 ± 8,25

10 ± 0

10 ± 0

10–100U/L

 AST

11,5 ± 5

11,5 ± 5,97

13 ± 2,58

26 ± 10,95

13,5 ± 5

20 ± 7,48

0–50 U/L

 ALP

108 ± 64,60

45 ± 6,63

132 ± 114,32

97 ± 43,50

122 ± 106,62

91,5 ± 69,19

23–212 U/L

Urinary values

 SG

1018,75 ± 4,79

1018,75 ± 2,5

1017,5 ± 2,89

1018,75 ± 2,5

1017,5 ± 5

1018,75 ± 2,5

1015–1060

 Proteins (mg/dL)

Neg

neg

neg

neg

neg

neg

neg

 Glucose (mg/dL)

Neg

neg

neg

neg

neg

neg

neg

 pH

6,13 ± 0,48

6125 ± 0,25

6125 ± 0,25

6125 ± 0,25

6,25 ± 2,89

6 ± 0

5,5–7,0

 Blood

Neg

neg

neg

neg

neg

neg

neg

 Ketones

Neg

neg

neg

neg

neg

neg

neg

 Nitrite

Neg

neg

neg

neg

neg

neg

neg

 Urobilinogen

Neg

neg

neg

neg

neg

neg

neg

 Ascorbic acid

Neg

neg

neg

neg

neg

neg

neg

  1. Abbreviations: ALT alanine aminotransferase, ALP alkaline phosphatase, AST Aspartate transaminase, Crea creatinine, MCHC mean corpuscular hemoglobin concentration, MCV Mean corpuscular volume, neg negative, P placebo group, RBC red blood cells, SG specific gravity, T treatment group, WBC white blood cells