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Table 3 Complete blood count, serum chemistry, and urinary values (mean ± SD) and range for eight beagles dogs included in the study at different time points

From: Food-specific sublingual immunotherapy is well tolerated and safe in healthy dogs: a blind, randomized, placebo-controlled study

Parameters Mean ± SD Range
Day 0 Day 70 Day 119
P T P T P T
Complete blood count values
 RBC 6,97 ± 0,72 6,39 ± 0,23 - - 7,39 ± 0,88 6,94 ± 0,04 6,20–8,70 milj/μl
 Haematocrit 47,8 ± 5,56 44,33 ± 1,99 - - 47,45 ± 8,04 46,03 ± 1,66 43,0–59,0%
 Haemoglobin 16 ± 2,21 14,88 ± 0,25 - - 16,68 ± 2,09 15,98 ± 0,49 14,0–20,0 g/dl
 MCV 68,57 ± 1,96 69,38 ± 2,23 - - 63,95 ± 4,09 66,33 ± 2,12 63,0–77,0 fl
 MCHC 33,37 ± 0,78 33,58 ± 1,55 - - 35,4 ± 2,05 34,7 ± 0,56 30,0–36,0 g/dl
 %Reticulocyte 0,43 ± 0,15 0,35 ± 0,19 - - 0,78 ± 0,55 0,55 ± 0,33 2-0%
 WBC 7556,67 ± 2091,28 7157,5 ± 1088,8 - - 6815 ± 2775,81 8180 ± 1047 6000–16000 /μl
 Neutrophil 66,23 ± 7,83 68,68 ± 1,41 - - 62,88 ± 10,23 64,88 ± 4,84 55,0–77,0%
 Lymphocyte 25,67 ± 6,13 20,98 ± 3,38 - - 22,23 ± 2,88 19,53 ± 2,31 12,0–35,0%
 Monocyte 4,2 ± 0,75 4,23 ± 0,59 - - 6,75 ± 1,62 8,05 ± 1,23 0,0–10,0%
 Eosinophil 3,17 ± 2,67 5,88 ± 3,52 - - 7,98 ± 13,04 7,28 ± 3,36 0,0–8,0%
 Basophil 0,7 ± 0,26 0,15 ± 0,1 - - 0,18 ± 0,17 0,28 ± 0,15 0–1%
 Platelet 395666,67 ± 137587,55 321500 ± 80172,73 - - 310500 ± 63321,93 248500 ± 29949,96 164000–510000
Biochemical values
 Urea 2,35 ± 0,68 2,45 ± 1,05 3,2 ± 1,10 3,55 ± 1,95 2,7 ± 0,42 3,1 ± 1,70 2,5–9,6 mmol/L
 Crea 28,5 ± 14,18 23,5 ± 8,54 32 ± 11,78 26 ± 9,80 24,5 ± 7,19 32 ± 28 44–159 mmol/L
 ALT 24 ± 4,90 26,5 ± 5,26 33,5 ± 8,22 35 ± 8,25 10 ± 0 10 ± 0 10–100U/L
 AST 11,5 ± 5 11,5 ± 5,97 13 ± 2,58 26 ± 10,95 13,5 ± 5 20 ± 7,48 0–50 U/L
 ALP 108 ± 64,60 45 ± 6,63 132 ± 114,32 97 ± 43,50 122 ± 106,62 91,5 ± 69,19 23–212 U/L
Urinary values
 SG 1018,75 ± 4,79 1018,75 ± 2,5 1017,5 ± 2,89 1018,75 ± 2,5 1017,5 ± 5 1018,75 ± 2,5 1015–1060
 Proteins (mg/dL) Neg neg neg neg neg neg neg
 Glucose (mg/dL) Neg neg neg neg neg neg neg
 pH 6,13 ± 0,48 6125 ± 0,25 6125 ± 0,25 6125 ± 0,25 6,25 ± 2,89 6 ± 0 5,5–7,0
 Blood Neg neg neg neg neg neg neg
 Ketones Neg neg neg neg neg neg neg
 Nitrite Neg neg neg neg neg neg neg
 Urobilinogen Neg neg neg neg neg neg neg
 Ascorbic acid Neg neg neg neg neg neg neg
  1. Abbreviations: ALT alanine aminotransferase, ALP alkaline phosphatase, AST Aspartate transaminase, Crea creatinine, MCHC mean corpuscular hemoglobin concentration, MCV Mean corpuscular volume, neg negative, P placebo group, RBC red blood cells, SG specific gravity, T treatment group, WBC white blood cells