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Table 2 Univariate Cox proportional-hazard analysis of B-cell lymphoma prognostic gene signatures in GSE43664 and GSE39365 datasets

From: Prognostic efficacy of the human B-cell lymphoma prognostic genes in predicting disease-free survival (DFS) in the canine counterpart

 

Coef

Exp (coef)

SE (coef)

z score

P

GSE43664 dataset

  Cfa.21188.1.S1_s_at: (CCND2)

-0.672

0.511

0.207

-3.24

0.0012

  Cfa.19972.1.S1_at: (BCL2L14)

-3.44

0.0321

1.26

-2.72

0.0065

  CfaAffx.18137.1.S1_at: (CR2)

-0.902

0.406

0.371

-2.43

0.015

  CfaAffx.4397.1.S1_x_at: (PAX5)

-1.03

0.357

0.446

-2.31

0.021

  Cfa.37.1.S1_at: (BIRC5)

-1.44

0.236

0.627

-2.3

0.021

  Cfa.16248.1.S1_at: (CCND1)

-0.505

0.604

0.257

-2.1

0.049

  Cfa.16217.1.S1_s_at: (CR2)

-0.527

0.59

0.272

-1.94

0.052

  Cfa.182.1.S2_at: (HLA-DQA1)

-0.467

0.627

0.241

-1.93

0.053

  Cfa.10937.1.S1_at: (LMO2)

-0.676

0.509

0.354

-1.91

0.056

  CfaAffx.6511.1.S1_at: (MYCN)

-1.19

0.304

0.63

-1.89

0.059

  Cfa.15639.1.A1_at: (TP53)

-0.373

0.688

0.202

-1.85

0.064

  Cfa.5536.1.A1_at: (MYCN)

-0.781

0.458

0.443

-1.76

0.078

  CfaAffx.18218.1.S1_at: (CR2)

-0.391

0.677

0.225

-1.74

0.083

  CfaAffx.18149.1.S1_s_at: (CR2)

-0.429

0.651

0.248

-1.73

0.083

  CfaAffx.18202.1.S1_s_at: (CR2)

-0.454

0.635

0.272

-1.67

0.095

  Cfa.19191.1.S1_at: (PDE4B)

-0.857

0.425

0.518

-1.65

0.098

  CfaAffx.4400.1.S1_at: (PAX5)

-1.65

0.192

1.05

-1.58

0.11

  CfaAffx.11868.1.S1_at: (MYBL1)

-1.21

0.297

0.773

-1.57

0.12

  Cfa.3707.1.A1_s_at: (FN1)

0.622

1.86

0.415

1.5

0.13

  Cfa.3800.2.S1_at: (CD44)

0.226

1.25

0.14

1.61

0.11

  CfaAffx.11235.1.S1_s_at: (CD44)

0.259

1.3

0.142

1.82

0.068

  Cfa.127.1.S1_s_at: (PLAU)

0.884

2.42

0.463

1.91

0.057

  Cfa.3707.2.S1_at: (FN1)

0.277

1.32

0.129

2.15

0.031

  CfaAffx.22155.1.S1_s_at: (FN1)

0.347

1.41

0.154

2.26

0.024

  Cfa.3707.3.S1_s_at: (FN1)

0.827

2.29

0.336

2.46

0.014

GSE39365 dataset

  Cfa.15826.1.S1_s_at: (BIRC5)

-0.832

0.435

0.477

-1.74

0.081

  Cfa.16248.1.S1_at: (CCND1)

-0.923

0.397

0.54

-1.71

0.088

  Cfa.5536.1.A1_at: (MYCN)

-2.44

0.0875

1.44

-1.69

0.091

  Cfa.10937.1.S1_at: (LMO2)

-0.825

0.438

0.516

-1.6

0.11

  Cfa.3619.1.S1_at: (CD38)

-0.804

0.448

0.512

-1.57

0.12

  Cfa.3619.1.S1_s_at: (CD38)

-0.605

0.546

0.39

-1.55

0.12

  CfaAffx.11868.1.S1_at: (MYBL1)

-1.76

0.171

1.16

-1.52

0.12

Clinical features (GSE39365 dataset)

  Age at diagnosis (years)

0.0774

1.08

0.0893

0.866

0.39

  Sex

0.165

1.18

0.576

0.287

0.77

  Grade

-1.04

0.354

0.68

-1.53

0.13

  1. Genes with z score higher than 1.5 or lower than -1.5 were listed. Exp (coef) indicates hazard ratio. Positive and negative z score denotes shorter and longer survival time respectively