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Table 2 Univariate Cox proportional-hazard analysis of B-cell lymphoma prognostic gene signatures in GSE43664 and GSE39365 datasets

From: Prognostic efficacy of the human B-cell lymphoma prognostic genes in predicting disease-free survival (DFS) in the canine counterpart

  Coef Exp (coef) SE (coef) z score P
GSE43664 dataset
Cfa.21188.1.S1_s_at: (CCND2) -0.672 0.511 0.207 -3.24 0.0012
Cfa.19972.1.S1_at: (BCL2L14) -3.44 0.0321 1.26 -2.72 0.0065
CfaAffx.18137.1.S1_at: (CR2) -0.902 0.406 0.371 -2.43 0.015
CfaAffx.4397.1.S1_x_at: (PAX5) -1.03 0.357 0.446 -2.31 0.021
Cfa.37.1.S1_at: (BIRC5) -1.44 0.236 0.627 -2.3 0.021
Cfa.16248.1.S1_at: (CCND1) -0.505 0.604 0.257 -2.1 0.049
Cfa.16217.1.S1_s_at: (CR2) -0.527 0.59 0.272 -1.94 0.052
Cfa.182.1.S2_at: (HLA-DQA1) -0.467 0.627 0.241 -1.93 0.053
Cfa.10937.1.S1_at: (LMO2) -0.676 0.509 0.354 -1.91 0.056
CfaAffx.6511.1.S1_at: (MYCN) -1.19 0.304 0.63 -1.89 0.059
Cfa.15639.1.A1_at: (TP53) -0.373 0.688 0.202 -1.85 0.064
Cfa.5536.1.A1_at: (MYCN) -0.781 0.458 0.443 -1.76 0.078
CfaAffx.18218.1.S1_at: (CR2) -0.391 0.677 0.225 -1.74 0.083
CfaAffx.18149.1.S1_s_at: (CR2) -0.429 0.651 0.248 -1.73 0.083
CfaAffx.18202.1.S1_s_at: (CR2) -0.454 0.635 0.272 -1.67 0.095
Cfa.19191.1.S1_at: (PDE4B) -0.857 0.425 0.518 -1.65 0.098
CfaAffx.4400.1.S1_at: (PAX5) -1.65 0.192 1.05 -1.58 0.11
CfaAffx.11868.1.S1_at: (MYBL1) -1.21 0.297 0.773 -1.57 0.12
Cfa.3707.1.A1_s_at: (FN1) 0.622 1.86 0.415 1.5 0.13
Cfa.3800.2.S1_at: (CD44) 0.226 1.25 0.14 1.61 0.11
CfaAffx.11235.1.S1_s_at: (CD44) 0.259 1.3 0.142 1.82 0.068
Cfa.127.1.S1_s_at: (PLAU) 0.884 2.42 0.463 1.91 0.057
Cfa.3707.2.S1_at: (FN1) 0.277 1.32 0.129 2.15 0.031
CfaAffx.22155.1.S1_s_at: (FN1) 0.347 1.41 0.154 2.26 0.024
Cfa.3707.3.S1_s_at: (FN1) 0.827 2.29 0.336 2.46 0.014
GSE39365 dataset
Cfa.15826.1.S1_s_at: (BIRC5) -0.832 0.435 0.477 -1.74 0.081
Cfa.16248.1.S1_at: (CCND1) -0.923 0.397 0.54 -1.71 0.088
Cfa.5536.1.A1_at: (MYCN) -2.44 0.0875 1.44 -1.69 0.091
Cfa.10937.1.S1_at: (LMO2) -0.825 0.438 0.516 -1.6 0.11
Cfa.3619.1.S1_at: (CD38) -0.804 0.448 0.512 -1.57 0.12
Cfa.3619.1.S1_s_at: (CD38) -0.605 0.546 0.39 -1.55 0.12
CfaAffx.11868.1.S1_at: (MYBL1) -1.76 0.171 1.16 -1.52 0.12
Clinical features (GSE39365 dataset)
Age at diagnosis (years) 0.0774 1.08 0.0893 0.866 0.39
Sex 0.165 1.18 0.576 0.287 0.77
Grade -1.04 0.354 0.68 -1.53 0.13
  1. Genes with z score higher than 1.5 or lower than -1.5 were listed. Exp (coef) indicates hazard ratio. Positive and negative z score denotes shorter and longer survival time respectively