Fig. 1
From: The using of a piglets as a model for evaluating the dipyrone hematological effects
Dynamics of changes in blood parameters after a single I.M. administration of dipyrone in piglets (n = 8) at a dose of 100 mg/kg. Changes in: white blood cells volume (a), red blood cells volume (b), hemoglobin (c), mean corpuscular volume (d), mean corpuscular hemoglobin (e), prothrombin time index (f), activated partial thromboplastin time (g), hematocrit (h). The period between -36 h and the value 0 represents the baseline - the value before drug administration. APTT – activated partial thromboplastin time (s); APTTratio- ratio of activated partial thromboplastin time; Hb – hemoglobin (g/dL); Hct – hematocrit (%); MCH – mean corpuscular hemoglobin (pg); MCV – mean corpuscular volume (fL); RBC – red blood cells volume (× 1012 L); WBC – white blood cells volume (× 109 L); PT – prothrombin time index (%); dashed line – arithmetic mean of baseline value