Table 1 Fold change in gene expression of selected immune genes after LPS challenge

Interferon stimulated genes

CXCL10

4

85

11

2

<0.001

LPS-pathway

TLR4

−2

2

3

1

<0.05

ISG15

2

43

17

4

<0.001

CD14

−4

1

1

1

<0.01

ISG20

1

9

7

3

<0.001

MyD88

−3

1

1

1

<0.05

IFIT1

1

9

3

1

<0.01

TRAF6

1

−2

−2

−2

<0.01

OAS1

1

14

7

2

<0.001

IFN-pathway

STAT1

1

2

2

1

<0.001

IFI6

1

5

5

3

<0.001

Cytokines and chemokines

IL1B

2

2

3

2

<0.01

MX1

1

17

11

2

<0.001

IL8

2

3

2

1

<0.01

Acute phase proteins

SAA3

4

80

412

10

<0.001

CCL3

3

2

4

1

<0.001

LF

3

5

17

2

<0.001

CCL5

−4

−3

−1

−5

<0.001

HP

8

14

54

1

<0.001

IL18

−3

−3

−3

1

<0.01

LCN2

2

2

3

−2

<0.01

IL1RN

1

14

7

1

<0.05

Enzymes

HSPA1A

1

3

13

1

<0.001

Other immune- related genes

TICAM

1

−3

−3

−2

<0.001

S100A9

1

8

18

3

<0.001

ITGB2

−2

−2

−4

1

<0.001

SOD2

−3

3

3

1

<0.001

MHCII

1

−2

−3

1

<0.001