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Table 4 Total masses of AHLs in the ear lavages of dogs with PaOE (Pseudomonas aeruginosa-associated OE), sampled in the course of treatment

From: Determination of N-acylhomoserine lactones of Pseudomonas aeruginosa in clinical samples from dogs with otitis externa

Day Week 1st dog
AHL mass [ng] Culture examination a
C4-HSL C6-HSL 3-oxo-C12-HSL P. aeruginosa Other bacteria
0 0 33.7 1.1 <0.3 +
7 1 26.7 1.1 <0.3 +
14 2 29.4 1.2 <0.3 +
21 3 15.3 1.2 <0.3 +
28 4 1.3 <0.3 <0.3 +
42 6 2.7 <0.3 <0.3 + (two strainsb)
56 8 20.7 <1 <0.3 + (two strains)
Day Week 2nd dog
AHL mass [ng] Culture examination
C4-HSL C6-HSL 3-oxo-C12-HSL P. aeruginosa Other bacteria
0 0 <0.3 <0.3 <0.3 +
7 1 8.2 <0.3 <0.3 + Proteus mirabilis
14 2 1.9 <0.3 <0.3 + (two strains)
21 3 21.2 1.6 <1 + (two strains) Proteus mirabilis
28 4 32.4 1.5 <1 + (two strains) Proteus mirabilis
42 6 3.1 <0.3 <0.3 + (two strains)
56 8 3.4 <0.3 <0.3 +
  1. aResults of culture examination are given for better understanding and are explained in the text
  2. bIndicating a secondary infection with a different P. aeruginosa strain, deteriorating the clinical condition of dogs and causing the increase of AHL content in the infected ear canal